Key references for COVID19,Cytokines and Cytokine Storm

Posted by Krishnan Allampallam on May 26, 2020 8:10:03 AM

COVID-19 & Cytokines

  1. Hennighausen et al., Activation of the SARS-CoV-2 receptor Ace2 by cytokines through pan JAK-STAT enhancers, Hennighausen L et al.
  2. Costela-Ruiz et al., SARS-CoV-2 infection: The role of cytokines in COVID-19 June 2020 disease
  3. Ronconi et al. SARS-CoV-2 and Kawasaki-Like Disease in children:  role of cytokines June 2020
  4. Mehta et al., Lancet, March, 2020. COVID-19: Consider cytokine storm syndromes and immunosuppression;
  5. Ricardo et al., Lancet, COVID-19 cytokine storm:  the interplay between inflammation and coagulation;
  6. John B Moore and Carl H. June, Science, May 2020, Cytokine release syndrome in severe COVID-19;
  1. Schett et al., Nat Rev Immunology, April, 2020. COVID-19: risk for cytokine targeting in chronic inflammatory diseases?
  2. Coperchini et al., May 2020, The Cytokine storm in COVID-19: An Overview of the involvement of the chemokine/chemokine-receptor system.

Treatment: Cytokine Storm

  1. Zhang et al., Int J Antimicrob Agents, March 2020, The cytokine release syndrome of severe COVID-19 and IL-6R antagonist Tocilizumab may be the key to reduce the mortality;
  2. Ye Q et al., J Infection, June 2020. The pathogenesis and treatment of the ‘Cytokine Storm’ in COVID-19.

Videos & Podcasts

  1. COVID-19 Insights: Rapid Death due to SARS-CoV (cytokine storm/massive immunomodulation) by Dr. Mobeen Medical Lectures
  2. Cytokine Storms and COVID-19 Severity, from John Hopkins Bloomberg School of Public Health , by Dr. Konig and Dr. Bettegowda
  3. Cytokine Storms in Rheumatic Diseases and COVID-19 by Dr. Randy Cron,

Updated on June 10th, 2020